1 answer

Why must some of your DNA be replicated in fragments? Please do not focus on how...

Question:

Why must some of your DNA be replicated in fragments? Please do not focus on how the DNA is replicated but tell me why some of it must be replicated in fragments.


Answers

DNA replication I'd directionAl it takesplace only in 5'-3' direction which is nothing but the direction of leading strand. Hence the replecation of the other synthesising strand that is lagging strand should takes place in opposite direction that is 3'-5'. But practically in lagging strand orientation 3'-5' replication doesn't occur. Hence DNA lagging strand folds to its back to form a loop at site of replication to cope up with leading strand direction and after finishing a small stretch of replication of lagging strand it unfolds to get its normal 3'-5' orientation and during this time replication pause for a while to leave a gap. After this it again form anot her loop forward to the previous one and replication begins.

Like wise lagging strand folds back and forth to produce discontinuous mode of replication in the 5'-3' direction to produce small fragments, on the other hand leading strand shows continous replication to produce single stretch of DNA.

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