1 answer

Le glucose Suusti dle! 6. The Vmax and KM values for an unusual hexokinase found in...

Question:

le glucose Suusti dle! 6. The Vmax and KM values for an unusual hexokinase found in Trypansoma cruzi (the causative agent of
antio- try to con OH 120 Po- O=P-0-16MMUZ 0- A bisphonate compound a. What type of inhibitor is bisphonate? b. The parasite h
le glucose Suusti dle! 6. The Vmax and KM values for an unusual hexokinase found in Trypansoma cruzi (the causative agent of Chagas disease) are shown in the presence and absence of a bisphonate inhibitor (structure shown). Without inhibitor With inhibitor KM (MM) Vmax (umol. min . mL-1) 90 0.30 125 0.12
antio- try to con OH 120 Po- O=P-0-16MMUZ 0- A bisphonate compound a. What type of inhibitor is bisphonate? b. The parasite hexokinase, unlike the mammalian enzyme, is not inhibited by glucose-6-phosphate but is inhibited by pyrophosphate (PP;). Is this observation consisten with your answer to part a? c. Might bisphonate be a good candie as a drug to treat the disease?

Answers


line-weaver Beste plots for Enzyme on Libiten Inlibile no In Lebar Compete the Inhibition KH increen Vina unakker Uncompetect 6 parasix heaolinase e is hebind ss PPÈ See not Glucose-6-phosphate & It is consisten te witha, sule, it seems intibition req

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