Answers
The result suggest that two x linked genes cause hemophilia when mutant. Individuals 1 & 2 are mutant in one gene ( call it gene A) and individuals 3 & 4 are mutant in the other gene ( gene B) .
.In 1952, an article in the British Medical Journal reported interesting differences in the behavior of blood plasma obtained from several individuals who suffered from X-linked recessive hemophilia. When mixed together, the cell-free blood plasma from certain combinations of individuals could form clots in the test tube. For example, the following table shows whether (+) or not (-) clots could form in various combinations of plasma from four individuals with hemophilia:
1 and 1 - 2 and 3 +
1 and 2 - 2 and 4 +
1 and 3 + 3 and 3 -
1 and 4 + 3 and 4 -
2 and 2 - 4 and 4 -
What do these data tell you about the inheritance of hemophilia in these individuals?
The result suggest that two x linked genes cause hemophilia when mutant. Individuals 1 & 2 are mutant in one gene ( call it gene A) and individuals 3 & 4 are mutant in the other gene ( gene B) .
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