# Current situation: 60-year-old adult man, begins to present diarrhea (> 3 days), dizziness, drowsiness, headache (strong),...

###### Question:

Current situation: 60-year-old adult man, begins to present diarrhea (> 3 days), dizziness, drowsiness, headache (strong), movement problems, vomiting (bloody), numbness and tingling of the extremities. He is taken by his wife to the hospital, in the triage consultation, he states that, due to chronic back pain, he self-medicated (for more than 3 months) with high doses (500mg / day) of a supposedly natural over-the-counter pain reliever . Unfortunately, this medication was found to contain diclofenac sodium.

1. what is Toxicokinetics. In this case, identify the phases of toxicokinetics in NSAID poisoning, explain step by step the mechanism of action and toxicity of diclofenac sodium by means of a diagram

2. What does Triage consist of? What is the assessment and general examination performed on the patient in this case of diclofenac sodium poisoning?

3.Consult the symptoms of sodium diclofenac poisoning, according to the time elapsed since ingesting the drug in poisoning by this drug. Please explain briefly what are its uses and its pharmacodynamics.

4. What are the complementary tests to identify diclofenac sodium poisoning? Consult and explain the clinical utility of a toxicological study, in which cases should a toxicological analysis be performed?

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