# 4) Eukaryotic genes require the compact chromatin fibers to uncoil for DNA to be accessed by...

###### Question:

4) Eukaryotic genes require the compact chromatin fibers to uncoil for DNA to be accessed by RNA polymerase. This chromatin remodeling is mediated by cis-acting elements and trans-acting factors. Describe the difference and name the two key players (one cis and one trans) that help to form the pre-initiation complex.

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