# 1. You are working on tissue engineering cartilage in a bioreactor by seeding mesenchymal stem cells...

###### Question:

1. You are working on tissue engineering cartilage in a bioreactor by seeding mesenchymal stem cells (MSCs) on a scaffold. a) What growth factor would you use to promote the MSC differentiation into chondrocytes? Fibroblast b) What are the advantages and disadvantages of directly injecting growth factors into the cell-seeded scaffold?
c) Can you propose another approach to provide growth factors to the tissue engineering construct? What are the advantages of your proposal? adatantages; grouth Factros can also scaffolds through the use of functional groups to chemical attached the Proteine. advantages ? d) Besides growth factors, what other regulators would you use to promote the growth of the tissue construct?

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